Cyclin-dependent kinase inhibitor 1

BE0009012ProteinHumansCDKN1A

Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest (PubMed:9106657). It is acted on by 2 drugs in DrugBank.

Gene name
CDKN1A
UniProtKB entry
P38936Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
164 residues · 18,119 Da
Also known as
CAP20 · CDK-interacting protein 1 · CDKN1 · CIP1 · MDA-6

Resolves to

Protein
UniProtP38936UniProt nameCDN1A_HUMAN
Gene
HGNCHGNC:1784NCBI Gene1026GeneCardsCDKN1A
Pharmacology
KEGGhsa:1026
Structure
PDB1AXCPDB2ZVVPDB2ZVW
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
29Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
25GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
33+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cyclin-dependent kinase inhibitor 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In