ATP synthase F(0) complex subunit e, mitochondrial

BE0009021ProteinHumansATP5ME

Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron... It is acted on by 1 drug in DrugBank.

Gene name
ATP5ME
UniProtKB entry
P56385Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
69 residues · 7,933 Da
Also known as
ATP synthase membrane subunit e · ATP5I · ATP5K · ATPase subunit e

Resolves to

Protein
UniProtP56385UniProt nameATP5I_HUMAN
Gene
HGNCHGNC:846NCBI Gene521GeneCardsATP5ME
Pharmacology
KEGGhsa:521
Structure
PDB8H9FPDB8H9JPDB8H9M
Drugs

What you can answer from here — as of June 26, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ATP synthase F(0) complex subunit e, mitochondrial, and which indications are they being tested in?

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