SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

BE0009035ProteinHumansSMARCE1

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). It is acted on by 1 drug in DrugBank.

Gene name: SMARCE1
UniProtKB entry: Q969G3Swiss-Prot
Cellular location: Nucleus
Residues / weight: 411 residues · 46,649 Da
Also known as: BAF57 · BRG1-associated factor 57

Resolves to

Protein

UniProtQ969G3UniProt nameSMCE1_HUMAN

Gene

HGNCHGNC:11109NCBI Gene6605GeneCardsSMARCE1

Pharmacology

KEGGhsa:6605

Structure

PDB6LTHPDB6LTJPDB7CYU

Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action

20GO termsFunction, process and component, as structured annotations

1Pfam domainDomain architecture mapped to Pfam families and clans

25+ReferencesStructured and connected to the statements they support

Which compounds in development act on SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1, and which indications are they being tested in?

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