Tropomyosin alpha-3 chain

BE0009038ProteinHumansTPM3

Binds to actin filaments in muscle and non-muscle cells. It is acted on by 1 drug in DrugBank.

Gene name
TPM3
UniProtKB entry
P06753Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
285 residues · 32,950 Da
Also known as
Gamma-tropomyosin · hTM5 · Tropomyosin-3 · Tropomyosin-5

Resolves to

Protein
UniProtP06753UniProt nameTPM3_HUMAN
Gene
HGNCHGNC:12012NCBI Gene7170GeneCardsTPM3
Pharmacology
KEGGhsa:7170
Structure
PDB6OTN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tropomyosin alpha-3 chain, and which indications are they being tested in?

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