Chromobox protein homolog 5

BE0009056ProteinHumansCBX5

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). It is acted on by 1 drug in DrugBank.

Gene name
CBX5
UniProtKB entry
P45973Swiss-Prot
Cellular location
Nucleus
Residues / weight
191 residues · 22,225 Da
Also known as
Antigen p25 · Heterochromatin protein 1 homolog alpha · HP1 alpha · HP1A

Resolves to

Protein
UniProtP45973UniProt nameCBX5_HUMAN
Gene
HGNCHGNC:1555NCBI Gene23468GeneCardsCBX5
Pharmacology
KEGGhsa:23468
Structure
PDB3FDTPDB3I3CPDB8UXQ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
21GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
35+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Chromobox protein homolog 5, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In