Keratin, type II cytoskeletal 2 epidermal

BE0009063ProteinHumansKRT2

Structural component of intermediate filaments in suprabasal keratinocytes of stratified epidermis. It is acted on by 4 drugs in DrugBank.

Gene name
KRT2
UniProtKB entry
P35908Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
639 residues · 65,433 Da
Also known as
CK-2e · Cytokeratin-2e · Epithelial keratin-2e · K2e · Keratin-2 epidermis

Resolves to

Protein
UniProtP35908UniProt nameK22E_HUMAN
Gene
HGNCHGNC:6439NCBI Gene3849GeneCardsKRT2
Pharmacology
KEGGhsa:3849
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Keratin, type II cytoskeletal 2 epidermal, how selective are they, and which programs against it are still in active trials?

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