Pigment epithelium-derived factor

BE0009068ProteinHumansSERPINF1

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. It is acted on by 1 drug in DrugBank.

Gene name
SERPINF1
UniProtKB entry
P36955Swiss-Prot
Cellular location
Secreted
Residues / weight
418 residues · 46,312 Da
Also known as
Cell proliferation-inducing gene 35 protein · EPC-1 · PEDF · Serpin F1

Resolves to

Protein
UniProtP36955UniProt namePEDF_HUMAN
Gene
HGNCHGNC:8824NCBI Gene5176GeneCardsSERPINF1
Pharmacology
KEGGhsa:5176
Structure
PDB1IMVPDB9J3PPDB9J3Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pigment epithelium-derived factor, how selective are they, and which programs against it are still in active trials?

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