Keratin, type II cytoskeletal 6A

BE0009088ProteinHumansKRT6A

Structural component of intermediate filaments in epithelial keratinocytes. It is acted on by 3 drugs in DrugBank.

Gene name
KRT6A
UniProtKB entry
P02538Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
564 residues · 60,045 Da
Also known as
CK-6A · CK-6D · Cytokeratin-6A · Cytokeratin-6D · K6A

Resolves to

Protein
UniProtP02538UniProt nameK2C6A_HUMAN
Gene
HGNCHGNC:6443NCBI Gene3853GeneCardsKRT6A
Pharmacology
KEGGhsa:3853
Structure
PDB5KI0
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Keratin, type II cytoskeletal 6A, how selective are they, and which programs against it are still in active trials?

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