KAT8 regulatory NSL complex subunit 3

BE0009091ProteinHumansKANSL3

Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation (PubMed:20018852, PubMed:33657400). It is acted on by 1 drug in DrugBank.

Gene name
KANSL3
UniProtKB entry
Q9P2N6Swiss-Prot
Cellular location
Nucleus
Residues / weight
904 residues · 95,991 Da
Also known as
KIAA1310 · Non-specific lethal 3 homolog · NSL complex protein NSL3 · NSL3 · PRTD

Resolves to

Protein
UniProtQ9P2N6UniProt nameKANL3_HUMAN
Gene
HGNCHGNC:25473NCBI Gene55683GeneCardsKANSL3
Pharmacology
KEGGhsa:55683
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on KAT8 regulatory NSL complex subunit 3, and which indications are they being tested in?

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