Nuclear receptor subfamily 1 group D member 1

BE0009347ProteinHumansNR1D1

Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. It is acted on by 2 drugs in DrugBank.

Gene name
NR1D1
UniProtKB entry
P20393Swiss-Prot
Cellular location
Nucleus
Residues / weight
614 residues · 66,805 Da
Also known as
EAR-1 · EAR1 · HREV · Rev-erbA-alpha · THRAL

Resolves to

Protein
UniProtP20393UniProt nameNR1D1_HUMAN
Gene
HGNCHGNC:7962NCBI Gene9572GeneCardsNR1D1
Pharmacology
IUPHAR/GtoPdb596KEGGhsa:9572
Structure
PDB1A6YPDB1GA5PDB1HLZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nuclear receptor subfamily 1 group D member 1, and which indications are they being tested in?

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