Nuclear receptor subfamily 1 group D member 2

BE0009348ProteinHumansNR1D2

Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. It is acted on by 2 drugs in DrugBank.

Gene name
NR1D2
UniProtKB entry
Q14995Swiss-Prot
Cellular location
Nucleus
Residues / weight
579 residues · 64,643 Da
Also known as
EAR-1R · Orphan nuclear hormone receptor BD73 · Rev-erb alpha-related receptor · Rev-erb-beta · RVR

Resolves to

Protein
UniProtQ14995UniProt nameNR1D2_HUMAN
Gene
HGNCHGNC:7963NCBI Gene9975GeneCardsNR1D2
Pharmacology
IUPHAR/GtoPdb597KEGGhsa:9975
Structure
PDB2V0VPDB2V7CPDB3CQV
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nuclear receptor subfamily 1 group D member 2, and which indications are they being tested in?

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