Botulinum neurotoxin type C

BE0009353ProteinClostridium botulinum

Botulinum neurotoxin type C Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequent heart or respiratory... It is acted on by 1 drug in DrugBank.

UniProtKB entry
P18640Swiss-Prot
Cellular location
Secreted
Residues / weight
1,291 residues · 148,865 Da
Also known as
3.4.24.69 · BoNT/C · BoNT/C1 · Bontoxilysin-C1 · Botulinum neurotoxin type C1

Resolves to

Protein
UniProtP18640UniProt nameBXC_CBCP
Structure
PDB2QN0PDB3DEBPDB3N7K
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
11GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Botulinum neurotoxin type C, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In