Botulinum neurotoxin type F

BE0009356ProteinClostridium botulinumbotF

Botulinum neurotoxin type F Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequent heart or respiratory... It is acted on by 1 drug in DrugBank.

Gene name
botF
UniProtKB entry
P30996Swiss-Prot
Cellular location
Secreted
Residues / weight
1,274 residues · 146,708 Da
Also known as
3.4.24.69 · BoNT/F · Bontoxilysin-F

Resolves to

Protein
UniProtP30996UniProt nameBXF_CLOBO
Structure
PDB2A8APDB2A97PDB3FIE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Botulinum neurotoxin type F, how selective are they, and which programs against it are still in active trials?

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