Very long chain fatty acid elongase 5

BE0009375ProteinHumansELOVL5

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. It is acted on by 2 drugs in DrugBank.

Gene name
ELOVL5
UniProtKB entry
Q9NYP7Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
299 residues · 35,293 Da
Also known as
2.3.1.199 · 3-keto acyl-CoA synthase ELOVL5 · Elongation of very long chain fatty acids protein 5 · ELOVL FA elongase 5 · ELOVL fatty acid elongase 5

Resolves to

Protein
UniProtQ9NYP7UniProt nameELOV5_HUMAN
Gene
HGNCHGNC:21308NCBI Gene60481GeneCardsELOVL5
Pharmacology
KEGGhsa:60481
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Metabolic reactionsDrug transformations it catalyses, substrate to product
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Very long chain fatty acid elongase 5, how selective are they, and which programs against it are still in active trials?

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