Dopamine receptor D2

BE0009377ProteinRatDrd2

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:1321233). It is acted on by 1 drug in DrugBank.

Gene name
Drd2
UniProtKB entry
P61169Swiss-Prot
Cellular location
Cell membrane
Residues / weight
444 residues · 50,903 Da
Also known as
D(2) dopamine receptor · Dopamine D2 receptor

Resolves to

Protein
UniProtP61169UniProt nameDRD2_RAT
Gene
NCBI Gene24318
Pharmacology
IUPHAR/GtoPdb215KEGGrno:24318
Drugs

What you can answer from here — as of September 08, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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127GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dopamine receptor D2, and which indications are they being tested in?

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