Serine/threonine-protein kinase pim-3

BE0009516ProteinHumansPIM3

Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. It is acted on by 6 drugs in DrugBank.

Gene name
PIM3
UniProtKB entry
Q86V86Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
326 residues · 35,891 Da
Also known as
2.7.11.1

Resolves to

Protein
UniProtQ86V86UniProt namePIM3_HUMAN
Gene
HGNCHGNC:19310NCBI Gene415116GeneCardsPIM3
Pharmacology
IUPHAR/GtoPdb2160KEGGhsa:415116
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase pim-3, how selective are they, and which programs against it are still in active trials?

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