Inositol phosphorylceramide synthase

BE0009553ProteinYeastAUR1

Catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis. It is acted on by 1 drug in DrugBank.

Gene name
AUR1
UniProtKB entry
O13332Swiss-Prot
Cellular location
Golgi apparatus
Residues / weight
471 residues · 53,458 Da
Also known as
2.-.-.- · Aureobasidin A resistance protein homolog · IPC synthase · Phosphatidylinositol:ceramide phosphoinositol transferase

Resolves to

Protein
UniProtO13332UniProt nameAUR1_CANAL
Gene
NCBI Gene3642617
Pharmacology
KEGGcal:CAALFM_C501240WA
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Inositol phosphorylceramide synthase, and which indications are they being tested in?

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