Envelope phospholipase OPG057

BE0009559ProteinVariola virus (isolate Human/India/Ind3/1967)OPG057

Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell. It is acted on by 1 drug in DrugBank.

Gene name
OPG057
UniProtKB entry
P33815Swiss-Prot
Cellular location
Virion membrane
Residues / weight
372 residues · 41,902 Da
Also known as
3.1.1.- · 37 kDa protein · Envelope protein F13 · p37K · Palmitoylated EV membrane protein

Resolves to

Protein
UniProtP33815UniProt namePG057_VAR67
Gene
NCBI Gene1486573
Pharmacology
KEGGvg:1486573
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Envelope phospholipase OPG057, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In