High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

BE0009580ProteinHumansPDE8B

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Gene name
PDE8B
UniProtKB entry
O95263Swiss-Prot
Residues / weight
885 residues · 98,978 Da
Also known as
3.1.4.53 · Cell proliferation-inducing gene 22 protein · HsPDE8B

Resolves to

Protein
UniProtO95263UniProt namePDE8B_HUMAN
Gene
HGNCHGNC:8794NCBI Gene8622GenBank32261241GeneCardsPDE8B
Pharmacology
IUPHAR/GtoPdb1308KEGGhsa:8622

What you can answer from here — as of September 03, 2024

3GO termsFunction, process and component, as structured annotations
Sign in
5Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
10+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In