Sodium channel protein type 7 subunit alpha

BE0009590ProteinHumansSCN7A

Sodium leak channel functioning as an osmosensor regulating sodium ion levels in various tissues and organs. It is acted on by 1 drug in DrugBank.

Gene name
SCN7A
UniProtKB entry
Q01118Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,682 residues · 193,492 Da
Also known as
Atypical sodium channel Nav2.1 · Nax channel · SCN6A · Sodium channel protein type VII subunit alpha

Resolves to

Protein
UniProtQ01118UniProt nameSCN7A_HUMAN
Gene
HGNCHGNC:10594NCBI Gene6332GeneCardsSCN7A
Pharmacology
KEGGhsa:6332
Structure
PDB7TJ8PDB7TJ9
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium channel protein type 7 subunit alpha, how selective are they, and which programs against it are still in active trials?

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