Cyclic AMP-dependent transcription factor ATF-4
BE0009604ProteinHumansATF4
Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGTAC[AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, and as master transcription factor during integrated stress...
- Gene name
- ATF4
- UniProtKB entry
- P18848Swiss-Prot
- Cellular location
- Nucleus
- Residues / weight
- 351 residues · 38,589 Da
- Also known as
- Activating transcription factor 4 · cAMP-dependent transcription factor ATF-4 · cAMP-responsive element-binding protein 2 · CREB-2 · CREB2
Resolves to
Pharmacology
What you can answer from here — as of September 03, 2024
Which compounds in development act on Cyclic AMP-dependent transcription factor ATF-4, and which indications are they being tested in?
Create a free account or log in to explore the full data card.
Create Account