Metal regulatory transcription factor 1

BE0009608ProteinHumansMTF1

Zinc-dependent transcriptional regulator of cellular adaption to conditions of exposure to heavy metals (PubMed:8065932). It is acted on by 1 drug in DrugBank.

Gene name
MTF1
UniProtKB entry
Q14872Swiss-Prot
Cellular location
Nucleus
Residues / weight
753 residues · 80,956 Da
Also known as
MRE-binding transcription factor · Transcription factor MTF-1

Resolves to

Protein
UniProtQ14872UniProt nameMTF1_HUMAN
Gene
HGNCHGNC:7428NCBI Gene4520GeneCardsMTF1
Pharmacology
KEGGhsa:4520
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metal regulatory transcription factor 1, how selective are they, and which programs against it are still in active trials?

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