Inositol polyphosphate 1-phosphatase

BE0009663ProteinHumansINPP1

Mg(2+)-dependent phosphatase that catalyzes the hydrolysis of the 1-position phosphate from inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate and participates in inositol phosphate metabolism. It is acted on by 1 drug in DrugBank.

Gene name
INPP1
UniProtKB entry
P49441Swiss-Prot
Residues / weight
399 residues · 43,998 Da
Also known as
3.1.3.57 · IPP · IPPase

Resolves to

Protein
UniProtP49441UniProt nameINPP_HUMAN
Gene
HGNCHGNC:6071NCBI Gene3628GeneCardsINPP1
Pharmacology
KEGGhsa:3628
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Inositol polyphosphate 1-phosphatase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In