Medium-chain fatty-acid--CoA ligase

BE0009670ProteinEscherichia coli (strain K12)fadK

Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.

Gene name
fadK
UniProtKB entry
P38135Swiss-Prot
Cellular location
Cell membrane
Residues / weight
566 residues · 62,759 Da
Also known as
6.2.1.- · ACS · Acyl-CoA synthetase · Fatty acyl-CoA synthetase FadK · ydiD

Resolves to

Protein
UniProtP38135UniProt nameFADK_ECOLI
Gene
NCBI Gene946213
Pharmacology
KEGGecj:JW5910

What you can answer from here — as of September 07, 2019

1Metabolic reactionDrug transformations it catalyses, substrate to product
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Medium-chain fatty-acid--CoA ligase, and which indications are they being tested in?

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