Sulfotransferase 1A2

BE0009673ProteinHumansSULT1A2

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is acted on by 3 drugs in DrugBank.

Gene name
SULT1A2
UniProtKB entry
P50226Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
295 residues · 34,309 Da
Also known as
2.8.2.1 · Aryl sulfotransferase 2 · P-PST 2 · Phenol sulfotransferase 2 · Phenol-sulfating phenol sulfotransferase 2

Resolves to

Protein
UniProtP50226UniProt nameST1A2_HUMAN
Gene
HGNCHGNC:11454NCBI Gene6799GeneCardsSULT1A2
Pharmacology
KEGGhsa:6799
Structure
PDB1Z29
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2Metabolic reactionsDrug transformations it catalyses, substrate to product
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sulfotransferase 1A2, how selective are they, and which programs against it are still in active trials?

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