Solute carrier family 12 member 5

BE0009674ProteinMouseSlc12a5

Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
Slc12a5
UniProtKB entry
Q91V14Swiss-Prot
Cellular location
Cell projection
Residues / weight
1,138 residues · 126,270 Da
Also known as
Electroneutral potassium-chloride cotransporter 2 · K-Cl cotransporter 2 · Kcc2 · Kiaa1176 · mKCC2

Resolves to

Protein
UniProtQ91V14UniProt nameS12A5_MOUSE
Gene
NCBI Gene57138
Pharmacology
KEGGmmu:57138
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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30GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 12 member 5, how selective are they, and which programs against it are still in active trials?

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