Melanocortin receptor 5

BE0009684ProteinHumansMC5R

G protein-coupled receptor for melanocyte-stimulating hormones (alpha- beta- and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8396929). It is acted on by 2 drugs in DrugBank.

Gene name
MC5R
UniProtKB entry
P33032Swiss-Prot
Cellular location
Cell membrane
Residues / weight
325 residues · 36,600 Da
Also known as
MC-2 · MC5-R

Resolves to

Protein
UniProtP33032UniProt nameMC5R_HUMAN
Gene
HGNCHGNC:6933NCBI Gene4161GeneCardsMC5R
Pharmacology
IUPHAR/GtoPdb286KEGGhsa:4161
Structure
PDB8INRPDB8IODPDB9K3H
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Melanocortin receptor 5, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In