Nucleoid-associated protein Lsr2

BE0009714ProteinMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)lsr2

DNA-bridging protein that has both architectural and regulatory roles (PubMed:18187505). It is acted on by 1 drug in DrugBank.

Gene name
lsr2
UniProtKB entry
P9WIP7Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
112 residues · 12,098 Da

Resolves to

Protein
UniProtP9WIP7UniProt nameLSR2_MYCTU
Gene
NCBI Gene885580
Pharmacology
KEGGmtu:Rv3597c
Structure
PDB2KNGPDB4E1PPDB4E1R
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nucleoid-associated protein Lsr2, how selective are they, and which programs against it are still in active trials?

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