Sulfotransferase 1A4

BE0009764ProteinHumansSULT1A4

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, (R)-adrenaline/epinephrine, (R)-noradrenaline/norepinephrine and serotonin) and phenolic and catechol drugs (PubMed:15358107, PubMed:29524394).

Gene name
SULT1A4
UniProtKB entry
P0DMN0Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
295 residues · 34,196 Da
Also known as
2.8.2.1 · Aryl sulfotransferase 1A3/1A4 · ST1A4 · Sulfotransferase 1A3/1A4

Resolves to

Protein
UniProtP0DMN0UniProt nameST1A4_HUMAN
Gene
HGNCHGNC:30004NCBI Gene445329GeneCardsSULT1A4
Pharmacology
KEGGhsa:6818

What you can answer from here — as of September 25, 2019

2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sulfotransferase 1A4, and which indications are they being tested in?

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