C-C chemokine receptor type 4

BE0009787ProteinHumansCCR4

High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. It is acted on by 2 drugs in DrugBank.

Gene name
CCR4
UniProtKB entry
P51679Swiss-Prot
Cellular location
Cell membrane
Residues / weight
360 residues · 41,402 Da
Also known as
C-C CKR-4 · CC-CKR-4 · CCR-4 · CCR4 · CMKBR4

Resolves to

Protein
UniProtP51679UniProt nameCCR4_HUMAN
Gene
HGNCHGNC:1605NCBI Gene1233GeneCardsCCR4
Pharmacology
IUPHAR/GtoPdb61KEGGhsa:1233
Drugs

What you can answer from here — as of November 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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11Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on C-C chemokine receptor type 4, how selective are they, and which programs against it are still in active trials?

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