1,5-anhydro-D-fructose reductase

BE0009800ProteinHumansAKR1E2

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity).

Gene name
AKR1E2
UniProtKB entry
Q96JD6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
320 residues · 36,589 Da
Also known as
1.1.1.263 · AF reductase · AKR1CL2 · AKRDC1 · Aldo-keto reductase family 1 member C-like protein 2

Resolves to

Protein
UniProtQ96JD6UniProt nameAKCL2_HUMAN
Gene
HGNCHGNC:23437NCBI Gene83592GeneCardsAKR1E2
Pharmacology
KEGGhsa:83592

What you can answer from here — as of December 24, 2019

2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 1,5-anhydro-D-fructose reductase, and which indications are they being tested in?

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