Aldo-keto reductase family 1 member B15
BE0009801ProteinHumansAKR1B15
Catalyzes the NADPH-dependent reduction of a variety of carbonyl substrates, like aromatic aldehydes, alkenals, ketones and alpha-dicarbonyl compounds (PubMed:21276782, PubMed:26222439).
- Gene name
- AKR1B15
- UniProtKB entry
- C9JRZ8Swiss-Prot
- Cellular location
- Mitochondrion
- Residues / weight
- 316 residues · 36,537 Da
- Also known as
- 1.1.1.- · 1.1.1.300 · 1.1.1.54 · Estradiol 17-beta-dehydrogenase AKR1B15 · Farnesol dehydrogenase
Resolves to
Pharmacology
What you can answer from here — as of December 24, 2019
Which compounds in development act on Aldo-keto reductase family 1 member B15, and which indications are they being tested in?
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