Catecholate siderophore receptor Fiu

BE0009806ProteinEscherichia coli (strain K12)fiu

Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It is acted on by 1 drug in DrugBank.

Gene name
fiu
UniProtKB entry
P75780Swiss-Prot
Cellular location
Cell outer membrane
Residues / weight
760 residues · 81,960 Da
Also known as
Ferric iron uptake protein · TonB-dependent receptor Fiu · ybiL

Resolves to

Protein
UniProtP75780UniProt nameFIU_ECOLI
Gene
NCBI Gene946246
Pharmacology
KEGGecj:JW0790
Structure
PDB6BPMPDB6BPNPDB6BPO
Drugs

What you can answer from here — as of December 24, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Catecholate siderophore receptor Fiu, how selective are they, and which programs against it are still in active trials?

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