Transient receptor potential cation channel subfamily M member 3

BE0009808ProteinHumansTRPM3

Constitutively active, non-selective divalent cation-conducting channel that is permeable to Ca(2+), Mn(2+), and Mg(2+), with a high permeability for Ca(2+). It is acted on by 1 drug in DrugBank.

Gene name
TRPM3
UniProtKB entry
Q9HCF6Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,732 residues · 197,569 Da
Also known as
KIAA1616 · Long transient receptor potential channel 3 · LTrpC-3 · LTRPC3 · Melastatin-2

Resolves to

Pharmacology
Structure

What you can answer from here — as of January 09, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transient receptor potential cation channel subfamily M member 3, how selective are they, and which programs against it are still in active trials?

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