Peroxisome proliferator-activated receptor gamma coactivator 1-beta

BE0009812ProteinHumansPPARGC1B

Plays a role of stimulator of transcription factors and nuclear receptors activities. It is acted on by 1 drug in DrugBank.

Gene name
PPARGC1B
UniProtKB entry
Q86YN6Swiss-Prot
Cellular location
Nucleus
Residues / weight
1,023 residues · 113,221 Da
Also known as
PERC · PGC-1-beta · PGC-1-related estrogen receptor alpha coactivator · PGC1 · PGC1B

Resolves to

Protein
UniProtQ86YN6UniProt namePRGC2_HUMAN
Gene
HGNCHGNC:30022NCBI Gene133522GeneCardsPPARGC1B
Pharmacology
KEGGhsa:133522
Structure
PDB3SP6PDB6D0Y
Drugs

What you can answer from here — as of January 16, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peroxisome proliferator-activated receptor gamma coactivator 1-beta, how selective are they, and which programs against it are still in active trials?

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