P2Y purinoceptor 1

BE0009816ProteinHumansP2RY1

Receptor for extracellular adenine nucleotides such as ADP (PubMed:25822790, PubMed:9038354, PubMed:9442040). It is acted on by 1 drug in DrugBank.

Gene name
P2RY1
UniProtKB entry
P47900Swiss-Prot
Cellular location
Cell membrane
Residues / weight
373 residues · 42,071 Da
Also known as
ADP receptor · P2Y1 · Purinergic receptor

Resolves to

Protein
UniProtP47900UniProt nameP2RY1_HUMAN
Gene
HGNCHGNC:8539NCBI Gene5028GeneCardsP2RY1
Pharmacology
IUPHAR/GtoPdb323KEGGhsa:5028
Structure
PDB4XNVPDB4XNWPDB7XXH
Drugs

What you can answer from here — as of January 22, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on P2Y purinoceptor 1, and which indications are they being tested in?

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