P2X purinoceptor 1

BE0009819ProteinHumansP2RX1

ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability (PubMed:10440098, PubMed:15056721, PubMed:20699225, PubMed:8834001, PubMed:8961184).

Gene name
P2RX1
UniProtKB entry
P51575Swiss-Prot
Cellular location
Cell membrane
Residues / weight
399 residues · 44,980 Da
Also known as
ATP receptor · P2X1 · Purinergic receptor

Resolves to

Protein
UniProtP51575UniProt nameP2RX1_HUMAN
Gene
HGNCHGNC:8533NCBI Gene5023GeneCardsP2RX1
Pharmacology
IUPHAR/GtoPdb478KEGGhsa:5023
Structure
PDB9B73PDB9B95PDB9C2A

What you can answer from here — as of January 22, 2020

11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on P2X purinoceptor 1, and which indications are they being tested in?

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