P2X purinoceptor 2

BE0009820ProteinHumansP2RX2

ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). It is acted on by 2 drugs in DrugBank.

Gene name
P2RX2
UniProtKB entry
Q9UBL9Swiss-Prot
Cellular location
Cell membrane
Residues / weight
471 residues · 51,754 Da
Also known as
ATP receptor · P2X2 · Purinergic receptor

Resolves to

Protein
UniProtQ9UBL9UniProt nameP2RX2_HUMAN
Gene
HGNCHGNC:15459NCBI Gene22953GeneCardsP2RX2
Pharmacology
IUPHAR/GtoPdb479KEGGhsa:22953
Structure
PDB9DDVPDB9DDWPDB9DDX
Drugs

What you can answer from here — as of January 22, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on P2X purinoceptor 2, how selective are they, and which programs against it are still in active trials?

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