P2Y purinoceptor 4

BE0009822ProteinHumansP2RY4

Receptor for UTP and UDP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. It is acted on by 4 drugs in DrugBank.

Gene name
P2RY4
UniProtKB entry
P51582Swiss-Prot
Cellular location
Cell membrane
Residues / weight
365 residues · 40,962 Da
Also known as
NRU · P2P · P2Y4 · UNR · Uridine nucleotide receptor

Resolves to

Protein
UniProtP51582UniProt nameP2RY4_HUMAN
Gene
HGNCHGNC:8542NCBI Gene5030GeneCardsP2RY4
Pharmacology
IUPHAR/GtoPdb325KEGGhsa:5030
Structure
PDB9K0K
Drugs

What you can answer from here — as of January 22, 2020

4DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on P2Y purinoceptor 4, and which indications are they being tested in?

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