P2Y purinoceptor 14

BE0009825ProteinHumansP2RY14

Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. It is acted on by 1 drug in DrugBank.

Gene name
P2RY14
UniProtKB entry
Q15391Swiss-Prot
Cellular location
Cell membrane
Residues / weight
338 residues · 38,971 Da
Also known as
G protein-coupled receptor 105 · GPR105 · KIAA0001 · P2Y14 · UDP-glucose receptor

Resolves to

Protein
UniProtQ15391UniProt nameP2Y14_HUMAN
Gene
HGNCHGNC:16442NCBI Gene9934GeneCardsP2RY14
Pharmacology
IUPHAR/GtoPdb330KEGGhsa:9934
Structure
PDB9J05PDB9J0BPDB9J0F
Drugs

What you can answer from here — as of January 22, 2020

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on P2Y purinoceptor 14, how selective are they, and which programs against it are still in active trials?

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