S-geranylgeranyl-glutathione receptor P2RY8

BE0009826ProteinHumansP2RY8

G protein-coupled receptor for S-geranylgeranyl-glutathione (GGG), an endogenous metabolite present in lymphoid tissues.

Gene name
P2RY8
UniProtKB entry
Q86VZ1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
359 residues · 40,635 Da
Also known as
P2Y purinoceptor 8 · P2Y8

Resolves to

Protein
UniProtQ86VZ1UniProt nameP2RY8_HUMAN
Gene
HGNCHGNC:15524NCBI Gene286530GeneCardsP2RY8
Pharmacology
KEGGhsa:286530
Structure
PDB9ECJ

What you can answer from here — as of February 11, 2025

2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on S-geranylgeranyl-glutathione receptor P2RY8, and which indications are they being tested in?

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