Delayed-rectifier potassium channel regulatory subunit KCNS1

BE0009833ProteinHumansKCNS1

Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values (PubMed:10484328).

Gene name
KCNS1
UniProtKB entry
Q96KK3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
526 residues · 58,371 Da
Also known as
Delayed-rectifier K(+) channel alpha subunit 1 · Delayed-rectifier potassium channel subunit Kv9.1 · hKv9.1 · Potassium voltage-gated channel modifier subfamily S member 1

Resolves to

Protein
UniProtQ96KK3UniProt nameKCNS1_HUMAN
Gene
HGNCHGNC:6300NCBI Gene3787GeneCardsKCNS1
Pharmacology
KEGGhsa:3787

What you can answer from here — as of December 03, 2024

7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Delayed-rectifier potassium channel regulatory subunit KCNS1, and which indications are they being tested in?

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