Hepcidin

BE0009858ProteinHumansHAMP

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. It is acted on by 3 drugs in DrugBank.

Gene name
HAMP
UniProtKB entry
P81172Swiss-Prot
Cellular location
Secreted
Residues / weight
84 residues · 9,408 Da
Also known as
HEPC · LEAP-1 · LEAP1 · Liver-expressed antimicrobial peptide 1 · PLTR

Resolves to

Protein
UniProtP81172UniProt nameHEPC_HUMAN
Gene
HGNCHGNC:15598NCBI Gene57817GeneCardsHAMP
Pharmacology
KEGGhsa:57817
Structure
PDB1M4EPDB1M4FPDB2KEF
Drugs

What you can answer from here — as of February 19, 2020

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Hepcidin, how selective are they, and which programs against it are still in active trials?

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