Sodium-coupled neutral amino acid symporter 1

BE0009870ProteinHumansSLC38A1

Symporter that cotransports short-chain neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane (PubMed:10891391, PubMed:20599747). It is acted on by 2 drugs in DrugBank.

Gene name
SLC38A1
UniProtKB entry
Q9H2H9Swiss-Prot
Cellular location
Cell membrane
Residues / weight
487 residues · 54,047 Da
Also known as
Amino acid transporter A1 · ATA1 · N-system amino acid transporter 2 · NAT2 · SAT1

Resolves to

Protein
UniProtQ9H2H9UniProt nameS38A1_HUMAN
Gene
HGNCHGNC:13447NCBI Gene81539GeneCardsSLC38A1
Pharmacology
KEGGhsa:81539
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-coupled neutral amino acid symporter 1, how selective are they, and which programs against it are still in active trials?

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