Sodium-coupled neutral amino acid symporter 2

BE0009871ProteinHumansSLC38A2

Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane (PubMed:10930503, PubMed:15774260, PubMed:15922329, PubMed:16621798). It is acted on by 1 drug in DrugBank.

Gene name
SLC38A2
UniProtKB entry
Q96QD8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
506 residues · 56,025 Da
Also known as
Amino acid transporter A2 · ATA2 · KIAA1382 · Protein 40-9-1 · SAT2

Resolves to

Protein
UniProtQ96QD8UniProt nameS38A2_HUMAN
Gene
HGNCHGNC:13448NCBI Gene54407GeneCardsSLC38A2
Pharmacology
KEGGhsa:54407
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-coupled neutral amino acid symporter 2, how selective are they, and which programs against it are still in active trials?

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