Thyroglobulin

BE0009873ProteinHumansTG

Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:17532758, PubMed:32025030). It is acted on by 2 drugs in DrugBank.

Gene name
TG
UniProtKB entry
P01266Swiss-Prot
Cellular location
Secreted
Residues / weight
2,768 residues · 304,788 Da
Also known as
Tg

Resolves to

Protein
UniProtP01266UniProt nameTHYG_HUMAN
Gene
HGNCHGNC:11764NCBI Gene7038GeneCardsTG
Pharmacology
KEGGhsa:7038
Structure
PDB6SCJPDB7B75PDB9I0O
Drugs

What you can answer from here — as of March 20, 2020

2DrugsApproved to experimental, with action, bond type and pharmacological action
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12Clinical trialsTrials of drugs acting on it, by phase and status
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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31+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thyroglobulin, how selective are they, and which programs against it are still in active trials?

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