Diacylglycerol kinase epsilon

BE0009932ProteinHumansDGKE

Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:15544348, PubMed:19744926, PubMed:21477596, PubMed:22108654, PubMed:23949095).

Gene name
DGKE
UniProtKB entry
P52429Swiss-Prot
Cellular location
Membrane
Residues / weight
567 residues · 63,927 Da
Also known as
2.7.1.107 · DAG kinase epsilon · DAGK5 · DGK-epsilon · Diglyceride kinase epsilon

Resolves to

Protein
UniProtP52429UniProt nameDGKE_HUMAN
Gene
HGNCHGNC:2852NCBI Gene8526GeneCardsDGKE
Pharmacology
KEGGhsa:8526

What you can answer from here — as of May 14, 2020

6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Diacylglycerol kinase epsilon, and which indications are they being tested in?

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