Diacylglycerol kinase zeta

BE0009934ProteinHumansDGKZ

Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:15544348, PubMed:18004883, PubMed:19744926, PubMed:22108654, PubMed:22627129, PubMed:23949095, PubMed:9159104).

Gene name
DGKZ
UniProtKB entry
Q13574Swiss-Prot
Cellular location
Nucleus
Residues / weight
928 residues · 103,980 Da
Also known as
2.7.1.107 · 2.7.1.93 · DAG kinase zeta · DAGK6 · DGK-zeta

Resolves to

Protein
UniProtQ13574UniProt nameDGKZ_HUMAN
Gene
HGNCHGNC:2857NCBI Gene8525GeneCardsDGKZ
Pharmacology
IUPHAR/GtoPdb3257KEGGhsa:8525
Structure
PDB5ELQ

What you can answer from here — as of May 14, 2020

6GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Diacylglycerol kinase zeta, and which indications are they being tested in?

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