Very long chain fatty acid elongase 2

BE0009936ProteinHumansELOVL2

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. It is acted on by 1 drug in DrugBank.

Gene name
ELOVL2
UniProtKB entry
Q9NXB9Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
296 residues · 34,584 Da
Also known as
2.3.1.199 · 3-keto acyl-CoA synthase ELOVL2 · ELG3 · Elongation of very long chain fatty acids protein 2 · ELOVL FA elongase 2

Resolves to

Pharmacology

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Very long chain fatty acid elongase 2, how selective are they, and which programs against it are still in active trials?

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