V-type proton ATPase subunit E 2

BE0009942ProteinHumansATP6V1E2

Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.

Gene name
ATP6V1E2
UniProtKB entry
Q96A05Swiss-Prot
Residues / weight
226 residues · 26,074 Da
Also known as
ATP6E1 · ATP6EL2 · ATP6V1EL2 · V-ATPase subunit E 2 · Vacuolar proton pump subunit E 2

Resolves to

Protein
UniProtQ96A05UniProt nameVATE2_HUMAN
Gene
HGNCHGNC:18125NCBI Gene90423GeneCardsATP6V1E2
Pharmacology
KEGGhsa:90423

What you can answer from here — as of May 15, 2020

1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type proton ATPase subunit E 2, and which indications are they being tested in?

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